Epigenetics: Can we transform our future?
Gene-environment interactions in the serotonergic system is an example of just one of the multiple neural signalling pathways that are affected in neuropsychiatric and neurological disorders. Dauncey, M.J. Genomic and Epigenomic Insights into Nutrition and Brain Disorders. Nutrients 2013 , 5 , 887-914. The Barcelona Brain Health Initiative (BBHI) will investigate if an individualized multi-dimensional intervention program can enhance cognitive functions and reduce the incidence of new future diagnoses. Cattaneo G, Bartrés-Faz D, Morris TP, Sánchez JS, Macià D, Tarrero C, Tormos JM and Pascual-Leone A (2018) The Barcelona Brain Health Initiative: A Cohort Study to Define and Promote Determinants of Brain Health. Front. Aging Neurosci. 10:321. doi: 10.3389/fnagi.2018.0032 1 A novel epigenetic clock, termed DNAm GrimAge has outperformed its predecessors in predicting the risk of mortality as well as a number of age-related morbidities. Higher DNAm GrimAge ass